University of South Carolina  DEPARTMENT GRAD PROGRAM SEMINARS UNIVERSITY

 
Dr Walden Ai Ph.D. Institute of Genetics, Chinese Academy of Sciences

Postdoctoral Fellowships
Washington University
University of Massachusetts
Columbia University
Assistant professor of Pathology, Microbiology and Immunology

  

 

 

Office: 803-253-5850
Lab: 803-733-3282
Fax: 803-733-3192
e-mail: waldenai
@gw.med.sc.edu

Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, SC 29208


Recent Publications

  Search PubMed for publications by Dr Walden Ai

1. Ai W, Zheng H, Yang X, Liu Y, Wang TC, Tip60 functions as a potential corepressor of KLF4 in regulation of HDC promoter activity. 2007. Nucleic Acids Res. 2007; 35(18):6137-49. Epub 2007 Sep 7.

2. Tu S, Chi AL, Lim S, Cui G, Dubeykovskaya Z, Ai W, Fleming JV, Takaishi S, Wang TC. Gastrin regulates the TFF2 promoter through gastrin-responsive cis-acting elements and multiple signaling pathways. Am J Physiol Gastrointest Liver Physiol. 2007 Mar1; [Epub ahead of print]


3. Cui G, Takaishi S, Ai W, Betz KS, Florholmen J, Koh TJ, Houghton J, Pritchard DM, Wang TC. Gastrin-induced apoptosis contributes to carcinogenesis in the stomach. Lab Invest. 2006 Oct; 86(10):1037-51.

4. Ai W, Takaishi S, Wang TC, Fleming JV. Regulation of L-histidine decarboxylase and its role in carcinogenesis. Prog Nucleic Acid Res Mol Biol. 2006; 81:231-70.

5. Ai W, Liu Y, Wang TC. Yin Yang 1(YY1) represses histiding decarboxylase (HDC) gene expression with SREBP-1a in part through an upstream Sp1 site. Am. J. Physiol. Gastrointest Liver Physiol, 2006 June, 290(6): G1096-1104.

6. Sinclair NF, Ai W, Bi, MX, Raychowdhury R. Koh TJ, and McLaughlin J. Gastrin Regulates the heparin Binding Epidermal-like Growth Factor Promoter Via a PKC/EGFR Dependent Mechanism. Am. J. Physiol. Gastrointest Liver Physiol. 2004 June; 286(6): G992-9.

7. Ai W, Liu Y, Langlois M, Wang TC. Kruppel-like factor 4 (KLF4) represses histidine decarboxylase (HDC) gene expression through an upstream Sp1 site and downstream gastrin responsive elements. J Biol Chem. 2004, Vol. 279(10): 8684-8693.

8. McLaughlin JT, Ai W, Sinclair NF, Colucci R, Raychowdhury R, Koh TJ, Wang TC. PACAP and Gastrin regulate the Histidine Decarboxylase Promoter via Distinct Mechanisms. Am. J. Physiol. Gastrointest Liver Physiol, 2004 Jan; 286(1):G51-9.

9. Tsang C.K., Bertram PG, Ai W, Drenan R and Zheng XF. Chromatin-mediated Regulation of Nucleolar Structure, RNA Polymerase I Localization and rDNA Transcription by Target of Rapamycin (TOR), EMBO J, 2003 Nov 17, 22(22):6045-56.

10. Ai W, Bertram PG, Tsang CK, Chan TF, Zheng XF. Regulation of Subtelomeric Silencing during Stress Response. Mol. Cell, 2002 Dec 20; 10(6):1295-305

11. Bertram PG, Choi JH, Carvalho J, Chan TF, Ai W, and Zheng XF. Convergence of TOR-Nitrogen and Snf1-Glucose Signaling Pathways onto Gln3. Mol Cell Biol. 2002 Feb; 22(4):1246-52.

12. Chan TF, Bertram PG, Ai W, Zheng XF. Regulation of APG14 expression by the GATA-type transcription factor Gln3p. J Biol Chem. 2001 Mar 2; 276(9):6463-7.

13. Bertram PG, Choi JH, Carvalho J, Ai W, Zeng C, Chan TF, Zheng XF. Tripartite regulation of Gln3p by TOR, Ure2p, and phosphatases. J Biol Chem. 2000, 275(46): 35727-33

14. Ai W, Narahari J. and Roman A. Yin yang 1 negatively regulates the differentiation-specific E1 promoter of human papillomavirus type 6. J Virol. 2000, 74(11): 5198-5205

15. Ai W, Toussaint E and Roman A. CCAAT displacement protein binds to and negatively regulates human papillomavirus type 6 E6, E7, and E1 promoters. J Virol. 1999, 73(5): 4220-4229

16. Ai W, Gong J, and Yu L. MAP kinase activation by mu opioid receptor involves phosphatidylinositol 3-kinase but not the cAMP/PKA pathway. FEBS Letters, 1999, 456: 196-200
 

 

Learn about the research of other faculty



     This page copyright 2006 The Board of Trustees of the University of South Carolina