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Office: 803 733 3180
Fax: 803 733 3192
E-mail:
pnagark
@med.sc.edu
Department of Pathology and Microbiology, University
of South Carolina School of Medicine, Columbia, SC 29208 |
Research Interests
Recent Publications
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Search PubMed for publications by Dr Prakash Nagarkatti
Recent Publications
1. McKallip,R.J., Nagarkatti, M. and Nagarkatti, P. Delta-9-tetrahydrocannabinol
enhances breast cancer growth and metastasis by suppression of the antitumor
immune response.
J Immunol. 174:3281-9, 2005.
2. Fisher, M.T., Nagarkatti, M. and Nagarkatti, P.S.
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) enhances negative selection of T
cells in the thymus while allowing auto-reactive T cells to escape deletion and
migrate to the periphery. Molecular Pharmacol. 67(1):327-35,2005.
3. McKallip,R.J., Szakal, A.K., Nagarkatti, P.S. and Nagarkatti, M. The role of
CD44 in SEB-induced hepatitis: CD44 deficiency leads to reduced lymphocyte
apoptosis resulting in increased liver damage. Infection and Immunity
73(1):50-61,2005.
4. Do, Y., McKallip R. J., Nagarkatti, P. S. and Nagarkatti, M. Activation
through cannabinoid receptots 1 and 2 on dendritic cells triggers NF-kappaB-dependent
apoptosis: Novel role for endogenous and exogenous cannabinoids in
immunoregulation. J. Immunol. 173:2373-2382, 2004.
5. Do, Y., Hegde, V., Nagarkatti, P. S. and Nagarkatti, M. Bryostatin-1 enhances
the maturation and antigen-presenting ability of murine and human dendritic
cells. Cancer Res. 64:6756-6765, 2004.
Representative Past Publications
6. McKallip, R.J., Do., Y., Fisher, M., Szakal, A.K., Gunthert, U., Nagarkatti,
P. S. and Nagarkatti, M. Targeted deletion of CD44v7 exon leads to decreased
endothelial cell injury and vascular leak syndrome induced by IL-2 activated
cytolytic lymphocytes J. Biol. Chem. 278 :43818-30, 2003
7. Zeytun, A., Nagarkatti, M. and Nagarkatti, P. S. Growth of FasL-bearing tumor
cells in syngeneic murine host induces apoptosis and toxicity in Fas+ organs.
Blood 95:2111-2117,2000
8. Kamath, A. B., Camacho, I., Nagarkatti, P. S. and Nagarkatti, M. Role of
Fas-Fas ligand interactions in 2, 3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced
immunotoxicity. Toxicol. Appl. Pharmacol. 160:141-155, 1999.
9. Nagarkatti, M., Hassuneh, M., Seth, A., Manickasundari, K. and Nagarkatti, P.
S. Constitutive activation of IL 2 gene in the induction of spontaneous in vitro
transformation and tumorigenicity of a T cell line. Proc. Natl. Acad. Sci. USA
91:7638-7642, 1994.
10. Hammond, D., Nagarkatti, P. S., Gote, L., Seth, A., Hassuneh, M. and
Nagarkatti, M. Double negative T cells from MRL lpr/lpr mice mediate cytolytic
activity when triggered through adhesion molecules and constitutively express
perforin gene. J. Exp.Med. 178:2225 2230, 1993.
11. Seth, A., Gote, L., Nagarkatti, M. and Nagarkatti, P. S. T cell receptor
independent activation of cytolytic activity of cytotoxic T lymphocytes mediated
through CD44 and gp90MEL-14. Proc. Natl. Acad. Sci. USA 88:7877 7881, 1991. |
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