IMMUNOLOGY

The Antibody Web  Article on web-based resources about antibodies by Stefan Dübel 
Antibody Resource Page

How to find an antibody
Antibody suppliers

The Recombinant Antibody Pages Lots of links etc. From University of Heidelberg, Molecular Genetics
Antibody Engineering Group How a monoclonal antibody is humanised.  The stages of producing single chain antibody.  Info from MRC, Cambridge
Humanization by Design Humanisation (also called reshaping or CDR-grafting) is now a well-established technique for reducing the immunogenicity of monoclonal antibodies (mAbs) from xenogeneic sources 
Antibodies - Structure and Sequence Summarizes useful information on antibody structure and sequence. It provides a query interface to the Kabat antibody sequence data, general information on antibodies and crystal structures and links to other antibody-related information
Immunoglobulin Structure/Function 

Images of Immunoglobulin Molecules 
IgG functions

These webpages on immunoglobulin structure and function have been prepared by Mike Clark, PhD, Cambridge University, Cambridge UK. 
The Immunology Link Page
CD antigens List of all those CD antigens, what they do and their other names
CD antigens Click on the CD number to see antibody spec sheets 
Immunohistochemistry
Immunoquery Immunohistochemistry query system. Determine the best panel of immunostains that will aid in the differential diagnosis of tumors, especially with the commercial explosion of available antibody reagents. To meet this need, the author has developed an immunohistochemistry database query system
On-Line Resources in Immunohistochemistry
Immunization Action Coalition Source of childhood, adolescent, and adult immunization information and hepatitis B educational materials
Introduction to Blood Morphology Lots of images
The Recombinant Antibody Pages S.Dübel, University of Heidelberg, Molecular Genetics. 
How to design an ELIZA 1996 Holiday Lectures Virtual Immunology Lab: ELISA Assay. From Howard Hughes Inst
The International Foundation for Helicobacter and Intestinal Immunology

VACCINES

The DNA Vaccine Web DNAvaccine.com is dedicated to giving the professional in the DNA Vaccine community access to the latest information in their field. In addition, we seek to establish a network of connections among these professionals for the purpose of maintaining a free flow of information.
CDC National Immunization Program

Vaccine Information Statements (VIS) 

Diseases that Vaccines Can Prevent in Infants and Children
and Adults. The Importance of Immunization 

Current printable (PDF) format files of the current Vaccine Information Statements

WHO Pages on Vaccines and Immunization From World Health Organization
The Vaccine Page The Vaccine Page provides access to up-to-the-minute news about vaccines and an annotated database of vaccine resources on the Internet.
Recommendations of the Advisory Committee on Immunization Practices (ACIP) From CDC

CYTOMETRY

Flow Cytometry at Univ Mass

Catalog of Free Flow Cytometry Software

 

UMass/Amherst Flow Cytometry Facility

BOOKS AND LECTURE NOTES FROM OTHER SOURCES

Kuby Immunology  4e by Richard A. Goldsby, Thomas J. Kindt and Barbara A. Osborne. W.H. Freeman. This Web site is designed to help students review key concepts from the textbook through interactive exercises and learning tools
The Biology Project

Eliza
Problem sets and tutorials

Western Blot

Nice animations
Understanding the Immune System 

This information is a collaboration of the National Cancer Institute and the National Institute of Allergy and Infectious Diseases. Very informative site
Immunology and AIDS  A laboratory exercise produced at the University of Arizona 
Edward Jenner and the Discovery of Vaccination
How Lymphocytes Produce Antibody From CellsAlive
Monoclonal Antibody Production Protocol  Click on the pictures or words to learn about details of monoclonal antibody production. 

IMMUNOLOGY  DATABASES
For general databases use link above

IMGT, the international ImMunoGeneTics database Integrated database specialising in Immunoglobulins (Ig), T cell receptors (TcR) and Major Histocompatibility Complex (MHC) molecules of all vertebrate species.  At present, IMGT includes two databases: IMGT/LIGM-DB, a comprehensive database of Ig and TcR from human and other vertebrates, with translation for fully annotated sequences, and IMGT/HLA-DB, a database of the human MHC referred to as HLA (Human Leucocyte Antigens). The IMGT server provides a common access to all Immunogenetics data.
Kabat Database  Sequences of Proteins of Immunological Interest
VBase Index Amino acid and nucleotide sequence alignments
Scale maps of the human immunoglobulin loci
Sequence alignment software (DNAPLOT)
Numbers of functional segments
Restriction enzyme cuts in V genes
PCR primers for rearranged V genes. From MRC Cambridge
RasMol & Chime: Molecular Visualization Freeware

Rotating RasMol Images

RasMol is free software for looking at molecular structures. It runs on Windows or Macintosh/PPC computers (also unix). Chime shows molecules like RasMol, but unlike RasMol, Chime shows molecules inside a web page. 
FRONTIERS IN BIOSCIENCE

Bioscience Gene Knockout List

Gene knockouts listed alphabetically according to the name of the gene 
The Transgenic/Targeted Mutation Database The Jackson Laboratory, Bar Harbor, Maine
TRANSGENIC RODENTS FOR THE STUDY OF MUTATION IN ANIMALS This web site is maintained at the Center for Environmental Health of the University of Victoria, BC, and describes the systems, gives references and abstracts of publications, is a repository of experimental results and a forum for researchers
Biomed Net Mouse Knockout  and Mutation Database Requires Biomed Net registration (free)
Bio-OnLine

Company Search

Searchable database of Biotech companies
Cytokine Family Database (dbCFC)

Cytokine Receptor Family Database

The Cytokine Family Database (dbCFC) is a collection of EST (Expressed Sequence Tag) records of cytokines deposited in the NCBI GenBank
PDB International repository for the processing and distribution of 3-D macromolecular structure data primarily determined experimentally by X-ray crystallography and NM

CYTOKINES

C O P E 
Cytokines Online Pathfinder Encyclopaedia 
Cytokines Web The Cytokines Web provides leading-edge scientific information about cytokines and their receptors, including 3-D structural information and topological and evolutionary relationships. It also contains information about
potential theraputic uses for some human cytokines. 
The International Cytokine Society 
Cell Signaling Networks Database  Cell Signaling Networks Data base (CSNDB) is a data- and knowledge- base for signaling pathways of human cells. It compiles the information on biological molecules, sequences, structures, functions, and biological reactions which transfer the cellular signals

COMMERCIAL SITES

Abcam The complete, free and independent antibody location service for researchers, providing 24 hour access to over 400 major companies' online catalogs. A really useful site
The Jackson Laboratory The Jackson Laboratory is an independent non-profit mammalian research laboratory.  The Jackson Laboratory  serves as a resource for genetic information with a
computerized database system that enables  efficient
access to a single comprehensive archive on basic research's most widely studied animal - the mouse

OTHER UNIVERSITY SITES

Developmental Studies Hybridoma Bank at The University of Iowa
 
 

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This page last changed on Tuesday, May 05, 2009
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